Trypanosoma (Herpetosoma) rangeli Tejera, 1920. Intracellular amastigote stages of reproduction in white mice.

T h e m e t h o d , si te , and s tage o f mul t ip l i ca t ion o f T r y p a n o s o m a ( H e r p e t o s o m a ) rangel i Te je ra , 1920 has n o t h i the r to b e e n k n o w n . "We h a v e n o w o b s e r v e d m a n y intracel lular nes t s o r p s e u d o c y s t s , con ta in ing a m a s t i g o t e s and t r y p o m a s t i g o t e s o f this paras i te in the heart , l iver , a n d sp leen o f suck l ing ( 5 . 0 g ) m a l e w h i t e m i c e ( N M R I s t ra in) i n o c u l a t e d i .p. w i t h 9 x 10 4 m e t a t r y p o m a s t i g o t e s / g b o d y we igh t f r o m a 12-day-old cu l tu re o f the "Dog-82" s t ra in o f T . rangel i . A t the p e a k o f pa ras i t emia ( 1 . 9 x 10 6 t r y p o m a s t i g o t e s / m l b l o o d , 3 d a y s pos t i nocu l a t i on ) va­ r i o u s t issues w e r e taken f o r s ec t ion ing a n d s ta ining. T h e hear t w a s m o s t inten­ sely paras i t ized . T h e amas t igo t e s w e r e r o u n d e d o r e l l ipso ida l , w i t h a r o u n d e d nuc leus a n d the k ine top las t in the f o r m o f a s t ra ight o r c u r v e d b a r ; the average m a x i m u m d i a m e t e r o f 50 m e a s u r e d a m a s t i g o t e s w a s 4.2 p. B i n a r y f i s s ion w a s seen in the nuc l eus a n d k ine top las t o f s o m e amas t i go t e s ; n o b l o o d t rypomas t i ­ g o t e s w e r e s een in d iv i s ion . T h e a b o v e charac te r i s t ics , as we l l as the l o c a t i o n o f the p s e u d o c y s t s in the t issues, a re s imi la r t o T . c ruz i . C o m p a r i s o n o f these re­ sults w i t h t h o s e r e p o r t e d f o r o t h e r H e r p e t o s o m a sugges t s t udy o f the t a x o n o m i c p o s i t i o n o f T . rangel i .